Identification and Quantitation of 11-Nor- 9-Tetrahydrocannabivarin-9-Carboxylic Acid, a Major Metabolite of 9-Tetrahydrocannabivarin
نویسندگان
چکیده
منابع مشابه
Novel automated extraction method for quantitative analysis of urinary 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid (THC-COOH).
An automated extraction method for extracting the major urinary metabolite of cannabis, 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) was developed on the four-probe Gilson ASPEC XL4trade mark solid-phase extraction (SPE) system. The method works on liquid-liquid extraction principles but does not require the use of SPE cartridges. The limits of detection and quantitation an...
متن کاملEffects of oxidizing adulterants on detection of 11-nor-delta9-THC-9-carboxylic acid in urine.
Bleach, nitrite, chromate, and hydrogen peroxide-peroxidase are effective urine adulterants used by the illicit drug users to conceal marijuana-positive results. Methods for detecting nitrite and chromate are available. Effects of other oxidizing agents that could possibly be used as adulterants and are difficult to detect or measure are presented in this report. Urine samples containing 40 ng/...
متن کاملA rapid sample-preparation technique for thin-layer chromatographic analysis for 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in human urine.
In this rapid TLC method of analysis for the urinary cannabinoid metabolite, 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH), hydrolyzed urine specimens are aspirated through a porous, alkyl-silica extraction layer located along the lower edge of a biphasic thin-layer chromatogram; THC-COOH is simultaneously extracted from the sample and concentrated on the TLC plate for subseq...
متن کاملThe diverse CB 1 and CB 2 receptor pharmacology of three plant cannabinoids : D 9 - tetrahydrocannabinol , cannabidiol and D 9 - tetrahydrocannabivarin
Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review focuses on the manner with which three of these compounds, ( )-trans-D-tetrahydrocannabinol (D-THC), ( )cannabidiol (CBD) and ( )-trans-D-tetrahydrocannabivarin (D-THCV), interact with cannabinoid CB1 and CB2 receptors. D-THC, the main psychotropic constituent of...
متن کاملMini - Review 11 - Nor - 9 - carboxy - ∆ 9 - tetrahydrocannabinol – a ubiquitous yet underresearched cannabinoid . A re - view of the literature
Synthetic ∆ 9 -tetrahydrocannabinol (THC), pharmaceutical grade herbal cannabis as well as formulations of well-defined cannabis extracts are available as registered medicines in several countries. It is generally accepted that the main central and peripheral pharmacological effects of THC are mediated by CB1 and CB2 cannabinoid receptors. Cytochrome P450-mediated oxidations of THC afford the n...
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ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2001
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/25.6.476